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Clamydia Jones [Explicit]

2008年1月31日 木曜日

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Interpreting Multiple Sclerosis Symptoms Properly

2008年1月31日 木曜日

Interpreting Multiple Sclerosis Symptoms Properly

The disease multiple sclerosis affects the body’s central nervous system. When the disease takes hold, multiple sclerosis symptoms can be painful and debilitating. This experience can be terrifying for a patient who previously lived a full and healthy life.


Sudden physical limitations and mood swings can be extremely difficult for the patient and their family. To help you understand what you or your loved one is going through, we’ll explain some of the most common symptoms of MS and give you some tips for coping them.


MS symptoms usually appear between the ages of 20 and 40. The onset of MS may be dramatic or so mild that a person doesn’t even notice any symptoms until far later in the course of the disease. Primary symptoms include impairment of the necessary transmission of electrical brain signals to muscles and the organs of the body.


The symptoms include weakness, tremors, tingling and numbness, loss of balance, vision impairment, paralysis, and bladder or bowel problems. Secondary symptoms result from primary symptoms. For example, paralysis can lead to bedsores, incontinence, and recurring urinary tract infections.


These symptoms can be treated, but the ideal goal is to avoid them by treating the primary symptoms. Tertiary symptoms are the social, psychological, and vocational complications associated with the primary and secondary symptoms. Depression, for example, is a common problem among people with MS.


Fatigue is the most common symptom of MS. It is typically present in the mid afternoon and may consist of increased muscle weakness, mental fatigue, sleepiness or drowsiness. Many MS patients report a sensitivity to heat that worsens when they go outside or take a shower. Muscle spasms are a common and often debilitating symptom of MS.


Spasticity usually affects the muscles of the legs and arms, and may interfere with a person’s ability to move those muscles freely. Many people with MS complain of dizziness and lightheadedness. These symptoms are caused by damage in the complex nerve pathways that coordinate vision and other inputs into the brain that are needed to maintain balance.


Perhaps the most frightening of all multiple sclerosis symptoms is cognitive impairment. Almost half of all MS patients report slowed thinking, difficulty concentrating and loss of short term memory. Some people experience problems with their vision, but these are moderate issues that do not include blindness.


Abnormal sensations can range from numbness to extreme pain. These symptoms can be treated. However, speech and swallowing problems, tremors and problems walking can be difficult to treat because these symptoms come as a result of damaged nerves.


Dealing with your multiple sclerosis symptoms does not have to be difficult or time consuming. You may not be able to do everything that you once enjoyed, but taking medication and making a few key lifestyle choices can ensure that you still live a full life. For more multiple sclerosis information, research the disease online or contact the Multiple Sclerosis Society.

Enrich your knowledge further about multiple sclerosis symptoms from Mike Selvon portal. We appreciate your feedback at our muscular dystrophy blog where a free gift awaits you.


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Witch Doctor – Ooh Eeh Ooh Ah Aah Ting Tang Walla Walla Bing

2008年1月30日 水曜日

Cartoons – Witch Doctor I do not own the song. How this got to two million views I’ll never know…

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Hiv/aids and Education

2008年1月29日 火曜日

Hiv/aids and Education

HIV/AIDS is the global issue of new era of science and technology and we should know that the problem of widespread AIDS is challenge for human survival. Children and young people need to be equipped with the knowledge, attitudes, values and skills that will help them face these challenges and assist them in making healthy life-style choices as they grow. Education delivered through schools is one of the ways through which children can be helped to face these challenges and make such choices.

Providing information about HIV (transmission, risk factors, how to avoid infection) is necessary, but not sufficient, to lead to healthy behavioral change. Programs that provide accurate information, to counteract the myths and misinformation, frequently report improvements in knowledge and attitudes, but this is poorly correlated with behavioral change related to risk taking and desirable behavioral outcomes. Education can be effective in the more difficult task of achieving and sustaining behavior change about HIV/AIDS. The schools can either be a place that practices discrimination, prejudice and undue fear or one that demonstrates society’s commitment to equity.School policies need to ensure that every child and adolescent has the right to life education; particularly when that education is necessary for survival and avoidance of HIV infection.

HIV infection is one of the major problems facing school-age children today. They face fear if they are ignorant, discrimination if they or a family member or friend is infected, and suffering and death if they are not able to protect themselves from this preventable disease.

It is estimated that 40 million people, worldwide, are living with HIV or have AIDS, at least a third of these are young people aged 15-24. In 1998 more than 3 million young people worldwide became infected including 590,000 children under 15. More than 8,500 children and young people become infected with HIV each day. In many countries over 50% of all infections are among 15-24 years old, who will likely develop AIDS in a period ranging from several months to more than 10 years.

Studies have shown the enormous impact HIV and AIDS have on the education sector and the quality of education provided, particularly in certain regions of the world such as Sub Saharan Africa. Consequences of the AIDS epidemic include a probable decrease in the demand for education, coupled with absenteeism and an increase in the number of orphans and school drop out, especially among girls. Girls are socially and economically more vulnerable to conditions that force people to accept risk of HIV infection in order to survive. A decrease in education for girls will have serious negative effects on progress made over the past decade toward providing an adequate education for girls and women. Reduced numbers of classes or schools, a shortage of teachers and other personnel, and shrinking resources for educational systems all impair the prospects for education.

Effective HIV/AIDS education and prevention is needed in all schools for all children so that no one is left ignorant. Yet in many places schools are apprehensive about providing sex education or discussions of sexuality because of cultural demands to protect adolescents from sexual experience. Women often lack skills needed to communicate their concerns with their sexual partners and to practice behaviors that reduce their risk of infection, such as condom use, which is often controlled by men.

The school can either be a place that practices discrimination, prejudice and undue fear or one that demonstrates society’s commitment to equity. School policies need to ensure that every child and adolescent has the right to HIV/AIDS education; particularly when that education is necessary for survival and avoidance of HIV infection.

A UNAIDS review (1997) of 53 studies which assessed the effectiveness of programs to prevent HIV infection and related health problems among young people concluded that sex education programs do not lead to earlier or increased sexual activity among young people, in fact the opposite seems to be true. 22 reported that HIV and/or sexual health education either delayed the onset of sexual activity, reduced the number of sexual partners or reduced unplanned pregnancies and STD rates. 27 studies reported that HIV/AIDS and sexual health neither increased nor decreased sexual activity, pregnancy or STD.

The review concluded that school based interventions are an effective way to reduce risk behaviors associated with HIV/AIDS/STD among children and adolescents.

There are three main objectives for this paper to integrate the education effectively with the HIV/AIDS preventions and other health aspects related with it.

These are as follows:

Objectives:

1) Health education focusing on HIV/AIDS prevention.

2) Raising awareness about HIV/AIDS among educators and learners.

3) Stimulate peer support and HIV/AIDS counseling in schools.

The main focus of the paper is to give the importance to the HIV/AIDS precaution with the health education raising the awareness about it among all the students as well as their teachers also and provide the supportive environment for the HIV/AIDS education for all.

Need of HIV/AIDS education:

In area such as HIV/AIDS prevention individual behavior, social and peer pressure, cultural norms and abusive relationships may all contribute to the health and lifestyle problems of children and adolescents. There is now increasing evidence that in tackling these issues and health problems, a healthy approach to HIV/AIDS and sex education works, and is more effective than teaching knowledge alone. T

here are numerous studies indicating that providing information about issues such as sex, STDs (Sexually Transmitted Diseases) and HIV (transmission, risk factors, how to avoid infection) is necessary, but not sufficient, to lead to healthy behavioral change (Hubley, 2000). Programs that provide accurate information, to counteract the myths and misinformation, frequently report improvements in knowledge and attitudes, but this is poorly correlated with behavioral change related to risk taking and desirable behavioral outcomes (Gatawa 1995, UNAIDS 1997a). HIV/AIDS with health education can be effective in the more difficult task of achieving and sustaining behavior change.

Health education with HIV/AIDS is widely applicable:

This problems largely affecting men and women as well as older children and adolescents, both this age group and younger children also face a wider range of health problems where education can play a vital role in sustainable prevention and management. Health education with HIV/AIDS programs plays a vital role in preventing infections. This is done through promoting knowledge of areas such as symptoms, transmission, and behaviors that are specifically relevant to many infection in each community; attitudes such as responsibility for personal, family and community health, confidence to change unhealthy habits; skills such as avoiding behaviors that are likely to cause infection, encourage others to change unhealthy habits, communicate messages about infection to families, peers and members of the community (WHO, 1996).

 This kind of health education with HIV/AIDS prevention focuses upon the development of Knowledge, Attitudes, Values, and Skills (including life skills such as inter-personal skills, critical and creative thinking, decision making and self awareness) needed to make and act on the most appropriate and positive health-related decisions. Health in this context extends beyond physical health to include psycho-social and environmental health issues.

This approach utilizes student centered and participatory methodologies, giving participants the opportunity to explore and acquire health promoting knowledge, attitudes and values and to practice the skills they need to avoid risky and unhealthy situations and adopt and sustain healthier life styles.

HIV/AIDS – a critical need for health education:

HIV/AIDS is an area where the scale and impact of the problem is such that the urgency of implementing preventative measures, including health education, is critical. Health education programs are being increasingly adopted as means of reaching children and young people to help halt the spread of this crippling epidemic. Studies from African countries show that children between the ages of 5 and 14 have the lowest prevalence of HIV infection. Below the age of 5 they are susceptible to mother to child transmission and after they become sexually active, the rate of infection increases rapidly – especially for girls (Kelly, 2000). Children aged 5-14 need to be reached at this critical stage in their lives and offer the ‘window of hope’ in stopping the spread of HIV/AIDS.

 Health Education with HIV/AIDS prevention Does Change Behavior:

There is now strong evidence from an increasing number of studies that health education HIV/AIDS prevention applied in an appropriate context, changes behavior – including behavior in sensitive and difficult areas where knowledge based health education has failed.

For example: Sexuality and HIV education –USA:

This study was implemented in 4 schools in New York City with 9th and 11th grade students (867 students), in intervention (AIDS prevention program) and control classes (no AIDS prevention program). The program focused on correcting facts about AIDS, teaching cognitive skills to appraise risk of transmission, increasing knowledge of AIDS-prevention resources, changing perceptions of risk-taking behavior, clarifying personal values, understanding external influences and teaching skills to delay intercourse and/or consistently use condoms. An evaluation carried out three months after the end of the program found that the intervention group showed the following positive behavioral outcomes when compared with the control group: decrease in intercourse with high risk partners, increase in monogamous relationships and an increase in consistent condom use. (Walter & Vaughan, 1993).

 HIV/AIDS prevention-Nigeria:

Health education programs are being implemented in many schools in Nigeria to increase levels of knowledge, influence attitudes and encourage safe sexual practices among secondary school students. A study to evaluate one such program was conducted comparing 223 students who received comprehensive sexual health education with 217 controls. Students in the intervention group received 6 weekly sessions lasting 2-6 hours, with activities including lectures, film shows, role-play stories, songs, debates, essays and a demonstration of the correct use of condoms. Following the intervention, students in the intervention group showed a greater knowledge and increased tolerance of people with AIDS compared to the control. The mean number of sexual partners also decreased in the intervention group, while the control group showed a slight increase. The program was also successful in increasing condom use (Fawole et al., 1999) Above mentioned studies shows that health education with HIV/AIDS prevention does change the behavior of students especially adolescents.

 Method for implementing Health Education with HIV/AIDS prevention:

Although there is strong evidence that HIV/AIDS prevention is effective when properly applied and supported, implementing this approach and achieving this success on a larger, countrywide scale is one of the greatest challenges to be faced.

To be effective, HIV/AIDS prevention programs must address the following areas:

•Reassure stakeholders that these messages are beneficial:

Talking and teaching about reproductive health and HIV/AIDS issues does not result in earlier initiation of sex or promiscuity. The evidence suggests that well implemented skills-based programs, conducted in an atmosphere of free discussion of all the issues, is likely to lead to young people delaying the initiation of intercourse and reducing the frequency of intercourse and number of sexual partners (Kirby et al. 1994, UNAIDS 1997a).

•Provide support to teachers: The lack of support for implementation of new programs is one of the most important factors affecting success. For most teachers both the content and methods of HIV/AIDS prevention programs are new and perhaps sensitive, and yet the approach has great potential to assist teachers both in their work and also their personal lives since HIV/AIDS is, of course, also affecting teachers. Sufficient support, training, practice and time needs to be available to teachers, in both pre- and in-service training sessions and workshops, to facilitate reflection and development of their own attitudes, and to motivate them to apply their new knowledge and skills, rather than continue with the more didactic, traditional teaching methods, which are often focused on information alone (Gatawa 1995, Gachuhi 1999). In addition, sufficient time and an appropriate place must also be given in the curriculum so that all students have access to HIV/AIDS prevention.

•Start early: As well as targeting adolescents, programs need to be targeted at children at an early age, with developmentally appropriate messages, before they leave school (Gachuhi 1999, Partnership for Child Development 1998). Because younger children are generally not sexually active, these programs will address the building blocks for healthy living and avoiding risk, rather than the very specific issues related to sexual relationships and HIV/AIDS which are progressively introduced to programs for older ages. However, the large number and diverse age range of children within primary schools is an enduring challenge, especially when addressing sensitive issues. Active and self-directed learning methods which are commonly used in education can be helpful in overcoming these classroom management issues to some extent.

•Provide a supportive environment: Schools need to have strong policies and a healthy supportive environment in terms of behavior of students towards each other, teachers and school personnel. Sexual abuse can occur in schools, with both boys and girls reporting abuse by school staff (Kinsman et al. 1999, Lowensen et al. 1996). Programs need to address this potential problem by training and supporting teachers, so that they can become role models rather than neutral or adverse figures in relation to sexual behavior.

•Respond to local needs: Many of the models for HIV/AIDS prevention have been developed in western, developed countries. The available evidence from developing countries, although more limited in scope than the studies from non-developing countries, supports skills-based health education for HIV/AIDS and reproductive health (Hubley, 2000). The main issue is that wherever programs are to be implemented they must be shaped to meet the local socio-cultural norms, values and religious beliefs, and need to include ongoing monitoring (Kirby et al 1994, UNAIDS 1999, Kinsman et al.1999).

Elements of a Health Education for HIV/AIDS prevention:

Reviews of school-based HIV/AIDS prevention programs (23 studies in the USA (Kirby et al. 1994), 37 other countries (reported in UNAIDS 1999) and 53 studies in USA, Europe and elsewhere (UNAIDS 1997a) have identified the following common characteristics of successful programs:

1.Focus on a few specific behavioral goals, (such as delaying initiation of intercourse or using protection), which requires knowledge, attitude and skill objectives.

2.Provision of basic, accurate information that is relevant to behavior change, especially the risks of unprotected intercourse and methods of avoiding unprotected intercourse. 3.Reinforcement of clear and appropriate values to strengthen individual values and group norms against unprotected sex.

4.Modeling and practice in communication and negotiation skills particularly, as well as other related “life skills”.

5.Use of Social Learning theories as a foundation for program development.

6.Addressing social influences on sexual behaviors, including the important role of media and peers.

7.Use of participatory activities (games, role playing, group discussions etc.) to achieve the objectives of personalizing information, exploring attitudes and values, and practicing skills.

8.Extensive training for teachers/implementers to allow them to master the basic information about HIV/AIDS and to practice and become confident with life skills training methods.

9.Support for reproductive health and HIV/STD prevention programs by school authorities, decision and policy makers, as well as the wider community.

10.Evaluation (e.g. of outcomes, design, implementation, sustainability, school, student and community support) so that programs can be improved and successful practices encouraged.

11.Age-appropriateness, targeting students in different age groups and developmental stages with appropriate messages that are relevant to young people. For example one goal of targeting younger students, who are not yet sexually active, might be to delay the initiation of intercourse, whereas for sexually active students the emphasis might be to reduce the number of sexual partners and use condoms.

12.Gender sensitive, for both boys and girls.

 Conclusions:

 Health Education with HIV/AIDS prevention offers an effective approach to equipping children and young people with the knowledge, attitudes and skills that they need to help them avoid risk taking behavior and adopt healthier life styles. The scope of health education means that it can be applied to a wide range of areas, especially STDs and HIV/AIDS prevention, but also including violence, substance abuse, unwanted situations such as early pregnancy and all areas where knowledge and attitudes play a critical role in promoting a healthy lifestyle for children and young people growing up in the 21st century. We can sum it in following points- •The constitutional rights of learners and educators must be protected equally.

•There should not be compulsory disclosure of HIV/AIDS status.

•No HIV positive learner or educator may be discriminated against.

 •Learners must receive education about HIV/AIDS and abstinence in the context of life- skills education as part of the integrated curriculum.

•Educational institutions should ensure that learners acquire age and context appropriate knowledge and skills to enable them to behave in ways that will protect them from infection.

•Educators need more knowledge of, and skills to deal with HIV/AIDS and should be trained to give guidance on HIV/AIDS.

Suggestions for implications for policies and programmes:

•Male and female condom promotion efforts need to recognize, identify and address gender issues including sexual and other forms of violence, that inhibit condom use.

•HIV/AIDS, peer education, and sex education programmes for adolescents that incorporate gender equality issues into their framework should be fostered. Such programmes should enable a better understanding of how norms related to masculinity and femininity may increase risky sexual behaviour, and help young people begin thinking about how to work towards equal and responsible relationships.

•Voluntary Counselling and Testing (VCT) services should take into account the risk of violence and other adverse consequences when evaluating different approaches to disclosure. For example, patients can be given the choice of counsellor-mediated disclosure if that would help minimise adverse consequences.

•Both men and women should be involved in Prevention of Mother to Child Transmission (PMtCT) programmes. Antenatal services can educate men about sexuality, fertility and HIV prevalence to raise their awareness and sense of responsibility. This would avoid reinforcing the belief that women alone are responsible for pregnancy and for HIV transmission to the infant.

•Community Home Based Care (CBBC) approaches need to include a special effort to promote the role of men as care-givers in the family and community, and to provide adequate support and guidance to enable male participation. At the very least, such programmes should acknowledge that reliance on “home care” is, at present, largely reliance on “women’s care”.

References:

1.Fawole, I.O., Asuzu, M.C., Oduntan, S.O., Brieger, W.R. (1999). A school-based AIDS education program for secondary school students in Nigeria: a review of effectiveness. Health Education Research – Theory & Practice, 14: 675-683.

 2.Gachuhi, D. (1999). The impact of HIV/AIDS on education systems in the Eastern and Southern Africa region and the response of education systems to HIV/AIDS: Life Skills Programs.

3.Gatawa, B.G. (1995). Zimbabwe: AIDS Education for schools. Case Study. UNICEF Harare Zimbabwe.

4.Hubley, J. (2000). Interventions targeted at youth aimed at influencing sexual behavior and AIDS/STDs. Leeds Health Education Database, April 2000.

5.Kelly, M.J. (2000). Standing education on its head: Aspects of schooling in a world with HIV/AIDS. Current Issues in Comparative Education. 3(1).

6.Kinsman, J., Harrison, S., Kengeya-Kayondo, J., Kanyesigye, E., Musoke, S. & Whitworth, J. (1999). Implementation of a comprehensive AIDS education program for schools in Masaka District, Uganda. AIDS CARE, 11(5): 591-601.

7.Kirby, D., Short, L., Collins, J., Rugg, D. et al. (1994). School-based programs to reduce sexual risk behaviors: a review of effectiveness. Public Health Reports, 109(3): 339-361.

8.Lowensen, R., Edwards, L. & Ndlovu-Hove, P. (1996). Reproductive health rights in Zimbabwe. Training and Research Support Centre (TARSC).

9.UNAIDS (1997a). Impact of HIV and sexual health education on the sexual behavior of young people: a review update.

10.UNAIDS (1997b). Learning and teaching about AIDS at school. UNAIDS technical update, October 1997.

11.Walter, H. & Vaughan, R. (1993). AIDS risk reduction among a multiethnic sample of urban high school students. JAMA, 270(6): 725-730.

12.WHO (1996). Preventing HIV/AIDS/STI and related discrimination: an important responsibility of health promoting schools. WHO series on school health, document six.

Sarita

Research Fellow (UGC-JRF)

Faculty of Education

Mahatma Gandhi Kashi Vidyapith

Varanasi,U.P., India


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Periodontitis as a Risk Factor in non-diabetic Patients with coronary artery disease

2008年1月28日 月曜日

Periodontitis as a Risk Factor in non-diabetic Patients with coronary artery disease

Introduction

 

Coronary artery disease (CAD) remains the principal cause of death in most countries, despite significant preventive and therapeutic advances. It has many known risk factors like, Hypertension, Hyperlipidemia, Diabetes mellitus, Positive Family history, Smoking and so on. But many

conditions increase risk of CAD yet, through atherosclerosis (1,3).

Recent studies illustrate the existence of a relation between periodontal disorders and coronary artery disease, which power the probable effect of periodontal disease as a risk factor for(CAD(4 and 5).Otherwise another were experienced insignificant relation between (CAD) and periodentitis(8-10). Periodontitis is associated with endotoxemia, leakage of lipopolysaccharides ( LPS )deriving from periodontal pathogens into circulation(4,20). LPS is one of the potent stimulators of systemic inflammation and intima wall macrophage-derived foam cell formation, and therefore it is considered a proatherogenic compound,

through the response to increasing levels of acute phase proteins (CRP) (7, 8 and 9) .

Also recent epidemiologic studies show that  high CRP as a risk factor is considered for cardiovascular events (10). Also, an intervention study statement on whether the treatment of gingival inflammation (periodentitis) leads to reduced CHD mortality is not done (6).

Patients and Methods

A cohort study was done on 152 patients referring to Mazandaran Heart Center in North of Iran between 2008-2009. Inclusion criteria: Age over the 40 years who’s Coronary artery disease as defined by previous or current detection of 50% stenosis of a main coronary artery by coronary angiography .Or no significant stenosis of coronary artery.

Exclusion criteria: Diabetic, Periodontal treatment and/or antibiotic therapy during the last 6 months, Pregnancy, Current alcohol or drug abuse, or psychological reasons that make study participation impractical

Drugs which are potential causal for gingival hyperplasia such as (Hydantoin, Nifedipine, Cyclosporin A, and other)

The people studied divided in two groups by coronary angiography results.. Demographic information were derived from questions asked during the interviewed to age, sex, literacy level, weight, LDL and HDL, exercise, , smoking, blood pressure for all the two groups. Then a periodontal examination was done (by general dentist and periodontitis) for all participants of the study, who was unaware from the result of patient’s angiography.

Coronary artery disease defined by stenosis  more than 50% lumen in at least one coronary artery in angiography .Periodontal disease is an inflammatory disease of tissues or teeth holder tissue that gradually causes the destruction of tissues and loss of teeth.
Clinical periodontal examination included measuring plaque (plaque terms), bleeding on examination with the probe (Barnett bleeding indexes), Probing packet depth at the mesial  , distal, Bucal, Palatal or Lingual surface of all teeth except the third molar has been done

and CAL (Clinical Attachment Level) was calculated.

Plaques were recorded according to Silness & loe index.  Plaque depth measuring, the entrance depth of probe in longitudinal axis of tooth and also CAL as mm is registered and the number of teeth remaining were recorded.

Plaque index (Silness & loe): accumulation of debries in gingival margins of tooth that is determined with the scale of 0 to 3.

0 = No plaque

1 =A film of plaque adhering to the free gingival margin and adjacent area of the tooth. The plaque may be observed in situ only after application of a disclosing solution or by using a probe on the tooth surface.

2 = moderate accumulation of soft deposits within gingival pocket, or on the tooth and gingival margin, that can be seen with the naked eye.

3 = an abundance of soft matter within the gingival pocket, on the tooth and gingival margin, in all these areas.

Modified papillary Bleeding Index (Barnett) bleeding after the probing of gums sulcus bleeding gums, diffuse marginal inflammation, and swollen red papillae is determined with  the  Scale of zero to 3   :

Zero: the lack of bleeding after 30 seconds

One: bleeding after 30 seconds

Two: bleeding 2 to 30 seconds

Three: bleeding less than 2 seconds

Gingival groove depth: Shallow crevice or space around the tooth bounded by the surface of the tooth on one side and the epithelium lining the free margin of the gingiva on the other, V shaped. Sulcus depth can be measured by a periodontal probe.Histologic depth  is about 1.8mm,probing depth is2-3 mm.

Table 1 – distribution of people with coronary heart disease and without coronary heart disease according to gender

 

CHD

 

 

 

 

Gender

 

Patients With CHD (percent)

 

 

Patients Without CHD(percent)

 

 

Total

 

 

 

Male

 

 

37

(44.6)

 

 

46

(55.4)

 

 

83

 

 

Women

 

 

39

(56.5)

 

 

30

(43.5)

 

 

69

 

 

Illiterate or elementary

 

 

51

(67.1)

 

 

25

(32.9)

 

 

76

 

 

Guidance school

 

10

(43.5)

 

 

13

(56.5)

 

 

23

 

 

High School

 

 

11

(44)

 

 

14

(56)

 

 

25

 

 

Higher diploma

 

 

4

(14.3)

 

 

24

(85.7)

 

 

28

 

 

 

Clinical Attachment Level: The amount of space between attached periodontal tissues and a fixed point, usually the cement enamel junction.

A measurement used to assess the stability of attachment as part of a periodontal maintenance program.

Statistical significance was set at 0.05, and the unit of analysiswas the person.. Bivariate relationships were assessed by t tests or Kolmogorov-Smirnovtests for continuous variables and Cochran Mantel-Haenszel 2 statistics and odds ratios and 95% CIs for categoricalvariables.. Potential confounders were basedon the literature and our previous findings on the relationshipbetween clinical periodontal disease and CAD. (13-20).

Result

152 patients were included in this study.

There were 54.6% (83)men and the 45.4% (69) were female. The mean age for case group was 51.1+/-7.3(mean+/-SD) and 51.3+/-10.3 years for

control group. In male participants, 37 patients (44.6%) had coronary artery disease and among women 39 cases (56.5%) had CAD, which sex difference was not significant  (p= 0.96) (Table 1).

The level of education and physical activity , has contrary effect on CAD and this difference was statistically significant (p <0.05). (Table 2,)

 

Table 6 – distribution of people with coronary heart disease and coronary heart disease based on GI.

 

 

CHD

GI

 

Number of people

With CHD (percent)

 

 

Number of people

Without CHD

(percent)

 

 

Total

 

 

Score 0

0

(0)

 

13

(100)

 

13

 

 

Score 1

 

5

(19.2)

 

21

(80.8)

 

 

 

26

 

 

 

Score 2

 

31

(55.4)

 

25

(44.6)

 

 

56

 

 

Score 3

 

40

(70.2)

 

17

(29.8)

 

 

57

 

 

Other risk factors comparable  hypertension, hyperlipidemia, and smoking were higher significantly in CAD group than the other group one (p <0.05) (table 3,4,5).The level of physical activity in patients with CAD is significant less than other group.(table 2)

 

Mean BMI in patients without coronary artery disease is 25.72±2.95 and the mean BMI in people with CAD are30.29±5.34 that this relationship is statistically significant (P <0.05) .

 

Table 2 – Distribution of people with coronary heart disease and without coronary heart disease according to sport

 

 

CHD

 

 

 

Exercise

 

Number of people

With CHD (percent)

 

 

Number of people

Without CHD

(percent)

 

 

Total

 

 

Loss of

Physical

Activity

 

66

(73.3)

 

 

24

(26.7)

 

 

90

Regular exercise

 

1

(3)

 

 

32

(97)

 

 

33

 

Irregular exercise

 

9

(31)

 

 

20

(69)

 

 

29

 

Table 3 – distribution of people with coronary heart disease without coronary heart disease by smoking

CHD

 

 

 

 

Cigarettes

 

Patients With CHD (percent)

 

 

Patients Without CHD

(percent)

 

 

Total

 

 

Smoking

 

 

32

(80)

 

 

8

(20)

 

 

 

40

 

 

 

Non-smoking

 

 

44

(39.3)

 

 

68

(60.7)

 

 

112

 

 

Table 4 – distribution of people with coronary heart disease without coronary heart disease based on HPL

 

CHD

 

 

 

Hyperlipidemi(TC,LDL)

 

Number of people

With CHD (percent)

 

 

Number of people

Without CHD

(percent)

 

 

Total

 

 

TC>250

LDL>180

 

 

34

(77.3)

 

10

(22.7)

 

44

 

TC<250

LDL<180

 

42

(38.9)

 

66

(61.1)

 

 

108

 

 

Table 5 – distribution of people with coronary heart disease without coronary heart disease based on history of hypertension

 

 

 

Heart   disease

 

 

 

 

Hypertension

 

Number of people

With heart disease (percent)

 

 

Number of people

Without heart disease

(percent)

 

 

Total

 

 

History of hypertension

 

 

 

51

(85)

 

 

9

(15)

 

 

60

 

 

Without History of hypertension

 

 

25

(27.2)

 

 

67

(72.8)

 

 

92

 

 

The gingival index( GI) average was higher in patients with CAD (70.2%) than control group(29.8%) ,as like Bleeding index(BI) and this difference is statistically significant. (P <0.05) (Table 6,7)

 

The relationship between Entrance depth of

probe and CAD was not statistically significant. P = 0.5 (Table 9)

Table 7 – Distribution individuals with coronary heart disease and coronary heart disease according to Index of bleeding

 

Heart      disease

 

 

Bleeding index

 

Number of people

With CHD (percent)

 

 

Number of people

Without CHD

(percent)

 

 

Total

 

 

Score 0

7

(28)

 

18

(72)

 

 

25

 

Score 1

 

17

(47.2)

 

19

(52.8)

 

 

36

 

Score 2

 

31

(59.6)

 

21

(40.46)

 

 

52

 

Score 3

 

21

(53.8)

 

18

(46.2)

 

 

39

 

 

 

 

 

 

Measurement of clinical attachment level more likely reflects periodontal disease. The statistically significant difference was found in the clinical attachment level

(p<0.005), where a higher mean value was in patients with coronary artery disease

(53.8%) compared with patients

without CAD (46.2%).(Table 10)

 

 

 

 

 

 

 

 

 

Table 8- Distribution of individuals with coronary heart disease without coronary heart disease based on depth of Probe entrance

 

 

 

Heart        disease

 

 

Entrance depth of probe

 

Number of people

With CHD (percent)

 

 

Number of people

Without CHD

(percent)

 

 

Total

 

 

2 mm

 

8

(40)

 

 

12

(60)

 

 

20

 

 

3 mm

20

(45.5)

 

24

(54.5)

 

 

44

 

 

4 mm

14

(41.2)

 

20

(58.8)

 

 

34

 

 

5 mm

6

(54.5)

5

(45.5)

 

 

11

 

 

6 mm

9

(81.8)

 

2

(18.2)

 

 

11

 

 

7 mm

13

(65)

 

7

(35)

 

 

20

 

 

8 mm

6

(50)

 

6

(50)

 

 

12

 

 

Table 9 – Distribution of individuals with coronary heart disease and without coronary heart disease based on the amount of clinical adhesion.

 

 

CAL

 

clinical attachment

Number of people

With CHD (percent)

 

Number of people

Without CHD

(percent)

 

Total

 

1 mm

0

(0)

1

(100)

 

 

1

 

 

2 mm

10

(43.5)

13

(56.5)

 

 

23

 

 

3 mm

20

(37)

34

(63)

 

 

54

 

 

4 mm

16

(61.5)

10

(38.5)

 

 

26

 

 

5 mm

15

(65.2)

8

(34.8)

 

 

23

 

6 mm

10

(58.8)

7

(41.2)

 

 

17

 

 

 

Coefficient of plaque index with entrance depth of Probe is 0.659 that is statistically significant (P <0.05)
Coefficient of  plaque index with clinical adhesion rate is 0.664 that is statistically significant (p<0.05)
Coefficient of bleeding index with entrance depth of probe is 0.685 that is statistically significant (p<0.05)
Coefficient of bleeding index with clinical adhesion rate is 0.686 that is  statistically significant (p<0.05)
coefficient of entrance depth of probe with clinical adhesion rate is 0.894 that is statistically significant (p<0.05) .

 

Conclusion

This study suggests a possible association between Periodontitis and CAD.

Since 3 main indices out of 4 indices for periodontal diseases such as swollen red papillae, bleeding gums, or diffuse marginalinflammation, correlated with increased risk of coronary artery disease in our research and most other studies, periodontal disease may be regarded as an independent risk factor for coronary artery disease.

 

 

Discussion

The present study demonstrated higher abnormal Periodontal Indices in patients with coronary artery disease than normal groups as independent risk factor.

Several theories exist to explain the link between periodontal disease and heart disease. One theory is that oral bacteria can affect the heart when they enter the blood stream, attaching to fatty plaques in the coronary arteries (heart blood vessels) and contributing to clot formation. Coronary artery disease is characterized by a thickening of the walls of the coronary arteries due to the buildup of fatty proteins. Blood clots can obstruct normal blood flow, restricting the amount of nutrients and oxygen required for the heart to function properly. This may lead to heart attacks.

Another possibility is that the inflammation caused by periodontal disease increases plaque build up, which may contribute to swelling of the arteries.

Researchers have found that people with periodontal disease are almost twice as likely to suffer from coronary artery disease as those without periodontal disease. (American Academy of periodontology,5)

The association between periodontitis and  CAD may be because of common risk factors such as smoking,diabet,male gender and socioeconomic factors ,but there is also good evidence of  periodontitis being an independent risk factor for CAD.(2,15)  Furthermore, periodontal pathogens have been identified in early as well as advanced atherosclerotic lesions. (16) There is also some evidence that periodontitis is associated with increased plasma concentrations of pro-atherogenic Lipoproteins (17, 18). A study done by Buhlin K. And colleagues on the Range 143 women aged 43 to 79 years of age with CAD as a case group and 50 women 45 to 77 years old without CAD. OPG (Orthopanogram) were obtained for all patients and they were matched as viewpoints of other risk factors. The result of this study was, the women with CAD had lower oral and dental health conditions than women without CAD and there has been a significant relationship between periodontal disease and CAD. (19,20)

However multivariableanalyses indicate that periodontal status is not significantlyassociated with CHD in either ever smokers or never smokers.

 

Clinical signs of periodontal disease werenot associated with CAD, whereas systemic antibody responsewas associated with CAD in ever smokers and never smokers. Thesefindings indicate that the quality and quantity of the hostresponse to oral bacteria may be an exposure more relevant tosystemic atherothrombotic coronary events than clinical measures.(21)

 

 

References

[1] Wood,D MS,FRCP,FRCPE,FPHM,FESC,et al,.Established and emerging Cardiovascular risk factors. A H J ,2001 Vol; 141,Num,2, S49-S57.

[2] Raquel Boix Martíneza; Javier Almazán Islaa; Ma José Medrano Alberoa. Mortalidad por insuficiencia cardíaca en España, 1977-1998. Rev Esp Cardiol. 2002 Mar;Vol:55,Num.3:219-26. RRRRRrR2002

[3] Wilson PW, DAgostino RB, levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories Circulation 1998 May 12; 97(18): 1837-47.

[4] Beck J, Garicia R, Heiss G,Vokonas PS,Offenbacher S. Periodontal disease and cardiovascular disease.J Periodontal .1996 Oct; 67:1123-37.

[5]Loesche WJ, Schork A, Terpenning MS,Chen YM, ,Kerr C,Dominguez BL. The relation ship between dental disease and cerebral vascular accident in elderly United States veterans. Ann Periodontal 1998Jul; 3(1):161-74.

[6] Hujoel, PP..Does chronic periodontitis cause coronary heart disease? A review of the literature. J Am Dental Assoc. 2002 Vol 133,No suppl._1, 31S- 36S.

[7] Offenbacher S.Beck JD.A Perspective on the potential cardio protective benefits of periodontal therapy. Am Heart J. 2005 Jun; 149(6): 950-4.

[8] Renvert S, Pettersson T, Ohlsson O, Persson GR. Bacterial profile and burden of periodontal infection in subjects with a diagnosis of acute coronary syndrome. J Periodontal. 2006 Jul; 77(7):1110-9

[9] Spahr A.,Klein E,Khuseyinova N,Boeckh C,Muche R,Kunze M,Rothenbacher D,Pezeshki G,Hoffmeister A,Koenig W. Periodontal infections and coronary heart disease: role of periodontal bacteria and importance of total pathogen burden in the Coronary Event and Periodontal disease (CORODONT) study. Arch Intern Med. 2006 Mar 13; 166(5): 554-9.

[10] Ridker PM, Hennekens CH, Buring JE, Rifai N. C- reactive protein and other markers of inflammation in the prediction of cardiovascular disease. N Engl J Med. 2000 Mar 23; 342(12):836-43.

[11] DeStefano F., Anda R.F., Kahn, H.S.,   Willamson, D.F. Russell CM .Dental disease and risk of coronary heart disease and mortality. BMJ. 1993 Mar 13; 306(6879): 688-91.

[12] Hujoel PP, Drangsholt M., Spiekerman C. DeRouen, T.A.Periodontal disease and coronary heart disease risk. JAMA. 2000 Sep 20; 284(11), 1406-10.

[13] Hujoel PP, Drangsholt M.., Spiekerman C. DeRouen, TA. Pre-existing cardiovascular disease and periodontitis: a follow-up study. Juornal of dental Research 2002 Mar; 81(3): 186-91.

[14] Wu T., Trevisan M., Genco R., Dorn J et al,.Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its fallow up study. Arch Intern Med. 2000 Oct 9;Vol: 160 (18), 2749-55.

[15] Janket SJ., Baird AE., Chuang SK., Jones JA. Meta- analysis of periodontal disease and risk of coronary heart disease and storke. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003 May; 95(5):559-69.

[16] Madianos PN., Bobetsis GA., Kinane DF. Is Periodontitis with an increased risk of coronary heart disease and preterm and/ or low birth weight births? J Clin Periodontal 2002; 29 Suppl 3:22-36.

[17] Silness J., Loe H.. Periodental Disease in Pregnancy: II.Correlation Between Oral Hygiene and Periodontal Condition. Acta Odontol Scand 1964 Feb; 22:121-35.

[18] Brigg JE.,.Mckeown.PP, Crawtord.VL,.Woodside.JV,.Stout.RW, Evans.A, and,.Linden GJ. Angiographically confirmed coronary heart disease and periodontal disease in middle-Aged Males. J Periodontal, 2006 Jan; 77(1):95-102.

[19] Buhlin K., Gustafsson A., Ahnve S., Janszky I., Tabrizi F., Klinge B., Oral Health in Woman With Coronary Heart disease. J Periodontology 2005 Apr;Vol. 76 ,N(4),Page: 544-50.

[20] Lopez R., Oyarzun M., Naranjo C., Cumsille F., Ortiz M., Baelum V. Coronary hearth disease and periodontitis- a case control study in Chilean adults, JClin Periodontal 2002 May; 29(5): 468-73

[20] Ozlem Fentoglu ,F.Yesim ,Bozkurt,

The Bi_Directional Relationship between

Periodontal Disease and Hyperlipidemia,

Eur.J.Dent.2008 Apr;2:142-146

[21] James D. Beck, PhD; Paul Eke, PhD, MPH, PhD; Gerardo Heiss, MD, MPH, PhD; Phoebus Madianos, DDS, PhD; David Couper, PhD; Dongming Lin, MS; Kevin Moss, AS; John Elter, DMD, PhD; Steven Offenbacher, DDS, PhD, MMSc Periodontal Disease and Coronary Heart Disease, Circulation. 2005;112:19-24


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Cancer (Healthy People 2010)

2008年1月28日 月曜日

Cancer (Healthy People 2010)

Goal

Reduce the number of new cancer cases as well as
the illness, disability, and death caused by cancer.

Overview
Cancer is the second leading cause of death in the United States. During 2000, an
estimated 1,220,100 persons in the United States were expected to be diagnosed
with cancer; 552,200 persons were expected to die from cancer.1 These estimates
did not include most skin cancers, and new cases of skin cancer are estimated to
exceed 1 million per year. One

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STIs: Gonorrhea & Chlamydia

2008年1月27日 日曜日

A UNC-TV segment on gonorrhea and chlamydia infections in North Carolina. Produced by the Science & Medical Journalism Program of UNC at Chapel Hill.
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buckhollywood.com PLEASE SUBSCRIBE! Big Brother 8 is the best show this summer! I love you Julie Chen! WHAT THE BUCK Thanks for featuring me You Tube!! Love Buck bb8dish.blogspot.com THIS LINK WORKS! SORRY

What are some nutritional induced diseases for dogs and cats?

2008年1月26日 土曜日

Question by Sydney: What are some nutritional induced diseases for dogs and cats?
I need to do a paper for my nutrition class and I need a disease on dogs that is a nutritional induced. Any ideas? I found this disease: Bloat (Gastric Dilatation – Volvulus) Can you name more nutritional induced diseases? Thank you!

Best answer:

Answer by JOAN W
Pano which is growing pains for large/giant breeds dogs. If pups are given too much protein & start growing quickly, pano or joint problems can develop. I’m including 2 links for you.

http://www.peteducation.com/article.cfm?c=2+1561&aid=466

http://www.greatdanelady.com/articles/feed_program_for_pano.htm

The 2nd one has a number of different articles about nutritional issues affecting giant breeds & your best bet for additional info.

Add your own answer in the comments!

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